Guggulu

Guggul is made from the sap (gum resin) of the Commiphora mukul tree, which is native to India. This tree has been used in Ayurvedic medicine for centuries, and Ayurvedic texts dating back to 600 BC recommend it for treating atherosclerosis.

Today guggul gum resin is used for arthritis, lowering high cholesterol, “hardening of the arteries” (atherosclerosis), acne and other skin diseases, and weight loss.

Treating some types of acne. Guggul seems to work about as well as the antibiotic tetracycline in the treatment of nodulocystic acne. Both treatments decrease pain, swelling , and redness (inflammation), and the number of acne outbreaks.

Obesity. Some research suggests that taking a combination of guggul, phosphate, hydroxycitric acid, and L-tyrosine, along with exercise and a reduced-calorie diet, might slightly reduce weight. However, most other research suggests that guggul does not affect body weight in overweight or obese people.

High cholesterol. There is inconsistent evidence about the effects of guggul on cholesterol. Taking 3000 or 6000 mg of guggul daily does not seem to lower total cholesterol or triglycerides, or raise high-density lipoprotein (HDL or “good') cholesterol in people with high cholesterol who eat a Western diet. However, guggul does seem to reduce cholesterol levels in people following an Indian diet.
Osteoarthritis. Early research suggests that taking 500 mg of guggul (containing 3.5% guggulsterones) three times daily might improve arthritis pain.
Rheumatoid arthritis. Early research suggests that taking guggul 3000 mg daily for 4 months can improve symptoms of rheumatoid arthritis.