Bacopa Aerial

Bacopa monnieri (L) Wettst (common name, bacopa) is a medicinal plant used in Ayurveda, the traditional system of medicine of India, as a nootropic. It is considered to be a “medhya rasayana”, an herb that sharpens the mind and the intellect. Bacopa is an important ingredient in many Ayurvedic herbal formulations designed to treat conditions such as memory loss, anxiety, poor cognition and loss of concentration. It has also been used in Ayurveda to treat inflammatory conditions such as arthritis. In modern biomedical studies, bacopa has been shown in animal models to inhibit the release of the pro-inflammatory cytokines TNF-α and IL-6. However, less is known regarding the anti-inflammatory activity of Bacopa in the brain.
1. Contains powerful antioxidants
Antioxidants are substances that help protect against cell damage caused by potentially harmful molecules called free radicals.

Research suggests that damage caused by free radicals is linked to many chronic conditions, such as heart disease, diabetes, and certain cancers (3Trusted Source).

Bacopa monnieri contains powerful compounds that may have antioxidant effects (4).

For example, bacosides, the main active compounds in Bacopa monnieri, have been shown to neutralize free radicals and prevent fat molecules from reacting with free radicals (5Trusted Source).

When fat molecules react with free radicals, they undergo a process called lipid peroxidation. Lipid peroxidation is linked to several conditions, such as Alzheimer’s, Parkinson’s, and other neurodegenerative disorders (6Trusted Source, 7Trusted Source).

Bacopa monnieri may help prevent damage caused by this process.

For example, a study showed that treating rats with dementia with Bacopa monnieri reduced free radical damage and reversed signs of memory impairment (8Trusted Source).
2. May reduce inflammation
Inflammation is your body’s natural response to help heal and fight disease.

However, chronic, low-level inflammation has been linked to many chronic conditions, including cancer, diabetes, and heart and kidney disease (9Trusted Source).

In test-tube studies, Bacopa monnieri appeared to suppress the release of pro-inflammatory cytokines, which are molecules that stimulate an inflammatory immune response (10Trusted Source, 11Trusted Source).

Also, in test-tube and animal studies, it inhibited enzymes, such as cyclooxygenases, caspases, and lipoxygenases — all of which play key roles in inflammation and pain (10Trusted Source, 11Trusted Source, 12Trusted Source).

What’s more, in animal studies, Bacopa monnieri had anti-inflammatory effects comparable to those of diclofenac and indomethacin — two nonsteroidal anti-inflammatory drugs commonly used to treat inflammation (12Trusted Source, 13Trusted Source).

Nevertheless, more research is needed to determine whether Bacopa monnieri reduces inflammation in humans.
3. May boost brain function
Research suggests that Bacopa monnieri may help enhance brain function.

For example, one study in mice showed that supplementing with Bacopa monnieri improved their spatial learning and ability to retain information (14Trusted Source).

The same study also found that it increased dendritic length and branching. Dendrites are parts of nerve cells in the brain that are closely linked to learning and memory (14Trusted Source).

Additionally, a 12-week study in 46 healthy adults observed that taking 300 mg of Bacopa monnieri daily significantly improved the speed of processing visual information, learning rate, and memory, compared with the placebo treatment (15Trusted Source).

Another 12-week study in 60 older adults found that taking either 300 mg or 600 mg of Bacopa monnieri extract daily improved memory, attention, and the ability to process information, compared with the placebo treatment (16Trusted Source).
4. May help reduce ADHD symptoms
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that is characterized by symptoms like hyperactivity, impulsivity, and inattentiveness (17Trusted Source).

Interestingly, research has shown that Bacopa monnieri may help reduce ADHD symptoms.

One study in 31 children aged 6–12 years found that taking 225 mg of Bacopa monnieri extract daily for 6 months significantly reduced ADHD symptoms, such as restlessness, poor self-control, inattention, and impulsivity in 85% of the children (18Trusted Source).

Another study in 120 children with ADHD observed that taking an herbal blend that contained 125 mg of Bacopa monnieri improved attention, cognition, and impulse control, compared with the placebo group (19Trusted Source).
5. May prevent anxiety and stress
Bacopa monnieri may help prevent anxiety and stress. It’s considered an adaptogenic herb, meaning that it increases your body’s resistance to stress (20Trusted Source).

Research suggests that Bacopa monnieri helps reduce stress and anxiety by elevating your mood and reducing levels of cortisol, a hormone that is closely linked to stress levels (21Trusted Source).

One rodent study showed that Bacopa monnieri had anti-anxiety effects comparable to those of lorazepam (benzodiazepine), a prescription medication used to treat anxiety (22Trusted Source).

However, human studies on Bacopa monnieri and anxiety show mixed results.

For example, two 12-week human studies found that taking 300 mg of Bacopa monnieri daily significantly reduced anxiety and depression scores in adults, compared with the placebo treatment (1Trusted Source, 15Trusted Source).

Yet, another human study found that treatment with Bacopa monnieri had no effect on anxiety (23Trusted Source).
6. May help lower blood pressure levels
High blood pressure is a serious health concern, as it places strain on your heart and blood vessels. This can weaken your heart and increase your risk of heart disease (24Trusted Source, 25Trusted Source).

Research suggests that Bacopa monnieri may help keep blood pressure within a healthy range.

In one animal study, Bacopa monnieri reduced both systolic and diastolic blood pressure levels. It did this by releasing nitric oxide, which helps dilate blood vessels, resulting in improved blood flow and lower blood pressure (26Trusted Source, 27Trusted Source).

Another study showed that Bacopa monnieri significantly lowered blood pressure levels in rats that had elevated levels, but it had no effect in rats that had normal blood pressure levels (28).

However, one 12-week study in 54 healthy older adults found that taking 300 mg of Bacopa monnieri daily had no effect on blood pressure levels (1Trusted Source).

Based on current findings, Bacopa monnieri may lower blood pressure in animals with high blood pressure levels. Nevertheless, more human research is required to confirm these effects.
7. May have anticancer properties
Test-tube and animal studies have found that Bacopa monnieri may have anticancer properties.

Bacosides, the active class of compounds in Bacopa monnieri, have been shown to kill aggressive brain tumor cells and inhibit the growth of breast and colon cancer cells in test-tube studies (29Trusted Source, 30Trusted Source, 31Trusted Source).

Additionally, Bacopa monnieri induced skin and breast cancer cell death in animal and test-tube studies (32Trusted Source, 33Trusted Source).

Research suggests that the high levels of antioxidants and compounds like bacosides in Bacopa monnieri may be responsible for its cancer-fighting properties (29Trusted Source, 34, 35).